Exosomes for Skin Rejuvenation London

Exosomes for skin rejuvenation delivers concentrated regenerative signals directly into the skin to stimulate collagen production, improve elasticity, and restore a smoother, firmer complexion. At PRP London Clinic, 33 Cavendish Square, London W1G, our GMC-registered medical team offers multiple exosome facial protocols tailored to your skin concerns and goals.

We use Purasomes NC150+ (Skin Nutri) and SGC100+ (Skin Glow) for non-autologous treatments, alongside MCT autologous exosomes produced from your own cells. For enhanced penetration and results, exosome microneedling protocols deliver exosomes through micro-channels directly into the dermis. Combination protocols with Standard PRP or Advanced PRP (MCT Plasma) are also available for comprehensive facial rejuvenation.

Vitale et al. (2025) demonstrated in a split-face study that exosome treatment for face combined with microneedling showed greater improvements in texture, hydration, elasticity, and pigmentation compared to microneedling alone at 30, 90, and 180 days post-treatment.

Every exosome facial london treatment is performed by a GMC-registered doctor with expertise in regenerative skin protocols.

Dr Bruno Amendola (GMC: 4346629) — MBCAM, International Postgraduate Degree in Aesthetic Medicine (Rome), Save Face Accredited. Internationally recognised for advanced skin rejuvenation with decades of experience across microneedling, chemical peels, and regenerative protocols.

Dr Mohamed Nafei (GMC: 7520509) — MBBS, PgDip Aesthetic Medicine, PgDip Endocrinology. Over 10 years of experience specialising in exosome and PRP protocols.

Dr Reem Nouri (GMC: 6149512) — MBBS, DRCOG, Advanced Aesthetic Medicine. Nearly 20 years of medical experience with a thorough approach to patient assessment and care.

Collagen and Elastin Stimulation

When delivered into the dermis, exosomes instruct fibroblasts to increase type I collagen and elastin production. This rebuilds the skin's structural scaffold, improving firmness and reducing the appearance of fine lines and wrinkles. The Shah et al. (2025) comprehensive review confirmed early evidence supporting efficacy of exosome for skin rejuvenation across multiple clinical indications.

Cellular Repair and Anti-Ageing

Exosomes carry growth factors, peptides, and RNA that activate cellular repair pathways, helping reverse accumulated photodamage and oxidative stress. They reduce inflammatory markers that accelerate skin ageing and support the skin's natural moisture barrier — restoring hydration and reducing transepidermal water loss.

Under-Eye Rejuvenation

Exosome under eye treatment targets the delicate periorbital area where fine lines, crepiness, and skin quality concerns are common. Exosomes delivered via micro-injection or microneedling stimulate localised collagen production without the volume or migration risks associated with fillers, making them suitable for patients seeking skin quality improvement rather than volumisation.

Purasomes Skin Variants

We use two Purasomes formulations for skin: NC150+ (Skin Nutri) for deep nourishment and structural repair, and SGC100+ (Skin Glow) for radiance, brightness, and texture refinement. Both contain 20 billion colostrum-derived exosomes with 20 growth factors, delivered via AMPLEX Plus technology. Your doctor selects the optimal variant based on your skin assessment.

MCT Autologous Exosomes for Skin

The MCT System produces autologous exosomes from your own cells using photobiomodulation and thermal biomodulation. For skin rejuvenation, this offers maximum biocompatibility and can be combined with MCT Plasma (Advanced PRP) for a comprehensive regenerative facial protocol.

Exosome Microneedling Combination

Exosome microneedling is a highly effective delivery method. Microneedling creates thousands of controlled micro-channels in the skin, allowing topically applied exosomes to penetrate deep into the dermis. This dual approach stimulates collagen production from the microneedling itself while maximising exosome absorption. Vitale et al. (2025) demonstrated that microneedling + exosomes achieved greater improvements in texture, hydration, and elasticity compared to microneedling alone.

Your exosome facial begins with a consultation to assess your skin concerns, including texture, elasticity, pigmentation, and specific areas of concern. On treatment day, the skin is cleansed and topical anaesthetic applied for comfort.

For micro-injection protocols, your doctor delivers the exosome solution via fine needles into targeted facial areas — including the face, neck, décolletage, hands, or under-eye region. For exosome microneedling protocols, the microneedling device is used first to create micro-channels, then the exosome solution is applied topically and massaged into the skin for deep dermal absorption.

For combination sessions with PRP, the PRP is administered first via injection, followed by exosome delivery. The entire appointment takes approximately 60 minutes. Post-treatment, mild redness similar to mild sunburn is expected, typically resolving within 1-3 days.

Our exosome for face treatment follows a structured clinical protocol designed for optimal skin rejuvenation outcomes.

Exosome treatments focus on regenerating skin quality from within, whilst fillers provide immediate structural volume. Many patients benefit from both approaches as part of a comprehensive plan.

Exosome facial cost at PRP London Clinic reflects the quality of exosome products, the expertise of our GMC-registered doctors, and our clinical setting at 33 Cavendish Square. See the pricing table below for all available protocols.

A course of 1-3 sessions is typically recommended for skin rejuvenation, with sessions spaced 4-6 weeks apart. A consultation determines the most appropriate protocol for your skin concerns and goals.

Exosome skin treatment is considered safe when performed by qualified medical professionals with verified products. Shah et al. (2025) confirmed that early clinical evidence supports a favourable safety profile for exosomes across aesthetic dermatology indications.

Side effects are typically mild, temporary, and related to the delivery method. Micro-injection may cause localised redness, minor swelling, or slight bruising resolving within 1-2 days. Microneedling combination may produce redness and mild flaking for 2-3 days. For autologous MCT protocols, the use of your own biological material minimises adverse reaction risk.

Products used at our clinic: Purasomes™ (Dermoaroma Group, Italy; 14 registered patents), MCT System (CE/MDR-certified), and Rein PRP™ (CE Class IIB, ISO 13485:2016) for combination protocols. All treatments are performed by GMC-registered doctors with emergency equipment on-site.

First 24-48 Hours

Avoid touching, rubbing, or applying make-up to the treated area for at least 12 hours (24 hours for microneedling combinations). Do not use active skincare ingredients (retinoids, AHAs, BHAs, vitamin C serums) for 48 hours. Avoid direct sun exposure, saunas, steam rooms, and strenuous exercise for 24-48 hours. Use only gentle, fragrance-free moisturiser and SPF 50 if going outdoors.

First Two Weeks

Continue using a gentle cleanser and moisturiser. Reintroduce active ingredients gradually after 72 hours. Apply SPF 50 daily. Mild dryness or flaking is normal after microneedling combinations and indicates healthy skin renewal. Avoid chemical peels, laser treatments, or other facial procedures until your next appointment.

Follow-Up

Your next session is typically scheduled 4-6 weeks later. Contact the clinic if you experience any unusual or persistent symptoms beyond the expected mild redness.

Exosome for face treatment is not suitable for patients with: active skin infection or inflammatory skin conditions at the treatment site, uncontrolled autoimmune conditions, pregnancy or breastfeeding, active malignancy, blood clotting disorders, recent isotretinoin use (within 6 months), or active cold sores (herpes simplex) in the treatment area. Patients with a history of keloid scarring should discuss this with their physician, particularly for microneedling combination protocols.

Individual results vary depending on age, skin type, lifestyle factors, sun exposure history, and biological response to treatment. A clinical consultation with one of our GMC-registered doctors is required before any treatment. All claims are supported by peer-reviewed research referenced in our medical citations. This content is for informational purposes and does not constitute medical advice. Content last reviewed: March 2026.

PRP London Clinic is located at 33 Cavendish Square, London W1G 0PW, moments from Oxford Circus and Bond Street stations. Our dedicated clinical setting provides a discreet, professional environment for exosome facial london patients. From standalone exosome skin treatments to advanced microneedling and PRP combination protocols, our medical team designs a personalised plan for your skin rejuvenation goals.

Discover how exosome for skin rejuvenation can restore texture, firmness, and radiance. Book a consultation with our GMC-registered medical team at PRP London Clinic for a personalised skin assessment and treatment recommendation.