Medical Review
Medically reviewed by Dr Mohamed NafeiQuick Navigation
Juläine is one of the newest collagen-stimulating injectables available in the UK, and interest in it is growing quickly. If you are researching Juläine before and after results, reading reviews, or trying to work out how it compares with Sculptra and Profhilo, this guide brings the key information together in one place.
Juläine® of Sweden is a poly-L-lactic acid (PLLA) biostimulator. Rather than adding instant volume like a dermal filler, it prompts your skin to build its own new collagen over the weeks and months after treatment, for a gradual and natural improvement in firmness and skin quality. You can find full details, pricing and safety information on our Juläine treatment page at our London clinic.
Juläine results: what to expect and when
Because Juläine works by stimulating your own collagen rather than filling a line directly, results are progressive. Most people do not see the final effect straight after a session. Instead, the improvement builds as new collagen forms.
A typical Juläine journey looks like this:
- First few days: any redness, mild swelling or small bruises from the injections settle.
- Weeks 2 to 6: the skin starts to feel firmer as early collagen production gets going. A course is usually spaced across this period, with sessions two to four weeks apart.
- 2 to 3 months: this is when most people notice clearer results, with firmer, better-quality skin and softer folds. The full result from a course is usually seen around three months after the last session.
Results are gradual by design, which is a big part of why Juläine tends to look natural. There is no sudden, obviously "done" change.
How often are top-ups needed?
Because the new collagen is your own, Juläine results are long-lasting. The manufacturer reports that results typically last between 12 and 24 months, though this varies with your age, skin condition and lifestyle. Most people have a maintenance session at some point within that window, often around once a year, to top up their results before the effect fully fades. Your doctor will recommend timing based on how your skin responds.
Juläine before and after
The clearest way to understand Juläine is to see it. The Juläine before and after images below are genuine clinical results from the official Juläine of Sweden portal, credited to the treating clinicians. They show the kind of gradual softening of the nasolabial folds and improvement in skin quality that PLLA biostimulation produces, rather than the instant change you would expect from a filler.
A few things stand out across these Juläine of Sweden before and after results. The change is subtle and skin-led, the folds soften rather than vanish overnight, and the improvement keeps building across a course of sessions. Individual results always vary, which is exactly why an in-person assessment matters.
Juläine reviews: what patients say
Juläine reviews are still relatively limited online, for a straightforward reason: it is a newer treatment, developed by Sweden’s Nordberg Medical and only recently available in UK clinics. That means there are fewer published Juläine treatment reviews than for a long-established option like Sculptra, so it is worth reading what you do find carefully.
Where Juläine reviews do exist, a few themes tend to come up. People like that the results look natural and build gradually, and that the treatment improves overall skin quality rather than just filling one area. The most satisfied reviews usually come from people who understood upfront that a biostimulator takes two to three months to show its full effect, so their expectations matched how the treatment actually works.
For reassurance about the clinic itself, rather than the product, verified patient reviews are the better guide. PRP London Clinic holds a 4.7-star rating from over 100 verified patients on Google and a 4.5-star rating on Trustpilot, across all of our treatments. We would always encourage you to read independent reviews on platforms like these, and to be cautious of any clinic that shows only glowing, unverifiable testimonials on its own website.
Juläine vs Sculptra
Juläine vs Sculptra is the most common comparison, because both are PLLA collagen biostimulators that work by stimulating your own collagen gradually. In truth they are more alike than different.
- Same core idea: both use poly-L-lactic acid to trigger natural collagen production, with results that build over two to three months and last many months.
- Sculptra is the long-established option, with the longest track record and the most published reviews and before and after results.
- Juläine is a newer PLLA bio-activator, developed and made in Sweden by Nordberg Medical and CE-marked, designed around uniform PLLA microspheres.
Is Juläine better than Sculptra?
Neither is universally better. They are close cousins, and the right choice depends on your skin, your goals and your doctor’s assessment and experience with each product. Sculptra’s longer track record reassures some people, while others are drawn to Juläine’s newer microsphere design. In practice, the skill and judgement of the doctor injecting matters more than the brand on the vial. You can read more on our Sculptra treatment page.
Juläine vs Profhilo
Juläine vs Profhilo is really a comparison of two different jobs. Profhilo is a hyaluronic acid injectable that hydrates the skin and gives a "glow", with results that appear more quickly but are shorter-lived. Juläine is a PLLA collagen biostimulator that works more slowly to build firmer, better-quality skin that lasts longer. A simple way to think about it is Profhilo for skin hydration and Juläine for collagen rebuilding. Some people use them at different stages for different goals, guided by their clinician. You can read more on our Profhilo treatment page.
Side effects and aftercare
Juläine side effects are usually mild and short-lived. The most common are redness, mild swelling, tenderness or small bruises at the injection sites, which typically settle within a few days.
Juläine aftercare is straightforward. Your doctor will give you specific advice for your treatment, but it generally includes:
- Following your clinician’s guidance, which may include a light facial massage with a moisturiser in the days after treatment.
- Avoiding strenuous exercise, very hot environments such as saunas, and alcohol for a day or two.
- Keeping the skin clean and protecting it with SPF.
Because Juläine is an injectable medical treatment, it should only be given by a qualified medical professional after a face-to-face assessment. At our clinic, every Juläine treatment is performed by a GMC-registered doctor.
Juläine and collagen banking
"Collagen banking" is one of the biggest skincare trends right now. The idea is simple: instead of waiting until skin has lost significant firmness, you start supporting collagen earlier, often in your 30s and 40s, to build a reserve for the future. We naturally lose collagen from our mid-20s onward, so the thinking is that maintaining it is easier than trying to rebuild it later.
Collagen-stimulating treatments like Juläine fit this trend well, because they prompt your body to make its own new collagen rather than adding temporary volume. Used sensibly and under medical guidance, a Juläine course can be part of a longer-term, preventative approach to skin quality rather than a one-off fix. It is not a magic bullet, and it works best alongside the basics: sun protection, not smoking, and a consistent skincare routine.
Considering Juläine?
If you are considering Juläine, the best next step is a face-to-face consultation, so a doctor can assess your skin and tell you whether it is right for you. Juläine at PRP London Clinic starts from £895 for the first vial, with your full plan confirmed at consultation. You can see pricing, safety information and how to book on our Juläine treatment page.
Frequently Asked Questions
How often are top-ups needed?
Juläine results are long-lasting because the collagen is your own, typically lasting between 12 and 24 months depending on your age, skin condition and lifestyle. Most people have a maintenance top-up at some point within that window, often around once a year, before the effect fully fades. Your doctor will advise on timing at your review.
How soon will I see results from Juläine?
Juläine works gradually. Most people notice clearer results around two to three months after treatment as new collagen forms, with the full effect of a course usually seen about three months after the final session.
Is Juläine better than Sculptra?
Neither is universally better. Both are PLLA collagen biostimulators that work in very similar ways. Sculptra has the longer track record, while Juläine is a newer Swedish PLLA product. The right choice depends on your skin, your goals and your doctor's assessment.
What is the difference between Juläine and Profhilo?
Profhilo is a hyaluronic acid injectable that hydrates the skin, with quicker but shorter-lived results. Juläine is a PLLA collagen biostimulator that builds firmer, better-quality skin more slowly, with longer-lasting results. They do different jobs and are sometimes used together.
Does Juläine have side effects?
Juläine side effects are usually mild and short-lived, most commonly redness, mild swelling, tenderness or small bruises at the injection sites that settle within a few days. It should only be given by a qualified medical professional after a face-to-face assessment.
Are there real Juläine before and after photos?
Yes. This guide includes genuine Juläine before and after results from the official Juläine of Sweden clinical portal, credited to the treating clinicians. They show gradual softening of the nasolabial folds and improved skin quality rather than an instant, filler-style change.